| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | HHLR Advisors Ltd. | 5,980,568 | 0 | 30,680,313.84 | 0.2489 | 7.3941 | 06/30/2025 |
| 2 | Ariose Capital Management Ltd. | 1,704,393 | 1,704,393 | 8,743,536.09 | 2.9525 | 2.1072 | 09/30/2025 |
| 3 | Candriam Belgium SA | 1,132,563 | 1,132,563 | 5,810,048.19 | 0.0157 | 1.4003 | 06/30/2025 |
| 4 | SG Americas Securities LLC | 876,353 | 54,312 | 4,495,690.89 | 0.0175 | 1.0835 | 06/30/2025 |
| 5 | Abaris Investment Management AG | 282,000 | 0 | 1,446,660 | 2.0446 | 0.3487 | 12/31/2024 |
| 6 | Two Sigma Advisers LP | 209,383 | -153,817 | 1,074,134.79 | 0.002 | 0.2589 | 06/30/2025 |
| 7 | UBS Securities LLC | 184,845 | -133,701 | 948,254.85 | 0.0004 | 0.2285 | 06/30/2025 |
| 8 | abrdn, Inc. | 136,471 | -26,109 | 700,096.23 | 0.0066 | 0.1687 | 06/30/2025 |
| 9 | BNP Paribas Financial Markets | 122,405 | 1,496 | 627,937.65 | 0.0004 | 0.1513 | 06/30/2025 |
| 10 | Two Sigma Investments LP | 113,262 | -97,104 | 581,034.06 | 0.001 | 0.14 | 06/30/2025 |
| 11 | Saint Olive Gestion SNC | 80,000 | 0 | 410,400 | 0.0939 | 0.0989 | 12/29/2023 |
| 12 | Alberta Investment Management Corp. | 74,723 | 0 | 383,328.99 | 0.0039 | 0.0924 | 06/30/2025 |
| 13 | Renaissance Technologies LLC | 63,700 | -100 | 326,781 | 0.0004 | 0.0788 | 06/30/2025 |
| 14 | Morgan Stanley & Co. LLC | 58,295 | 23,478 | 299,053.35 | 0.0001 | 0.0721 | 06/30/2025 |
| 15 | Geode Capital Management LLC | 54,562 | 32,525 | 279,903.06 | 0 | 0.0675 | 06/30/2025 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | SPDR Portfolio Emerging Markets ETF | 271,000 | 271,000 | 1,390,230 | 0.0095 | 0.3351 | 09/30/2025 |
| 2 | Abaris Emerging Markets Equity | 124,000 | 0 | 636,120 | 5.1204 | 0.1533 | 04/30/2024 |
| 3 | ALPS Barrons 400 ETF | 111,490 | 111,490 | 571,943.7 | 0.3144 | 0.1378 | 09/30/2025 |
| 4 | Abaris Biotechnology Opportunities | 100,000 | 0 | 513,000 | 2.2454 | 0.1236 | 12/31/2024 |
| 5 | BSO Bio Sante | 80,000 | 0 | 410,400 | 0.1466 | 0.0989 | 12/29/2023 |
| 6 | Abaris Defensive Equity | 58,000 | 0 | 297,540 | 1.1201 | 0.0717 | 10/31/2023 |
| 7 | Fidelity Nasdaq Composite Index Fund | 54,562 | 32,525 | 279,903.06 | 0.0013 | 0.0675 | 08/31/2025 |
| 8 | SPDR S&P Emerging Markets Small Cap ETF | 52,900 | 52,900 | 271,377 | 0.0369 | 0.0654 | 09/30/2025 |
| 9 | abrdn Healthcare Opportunities Fund | 43,738 | 0 | 224,375.94 | 0.0263 | 0.0541 | 08/31/2025 |
| 10 | DFA Emerging Markets Social Core Equity Portfolio | 18,909 | 0 | 97,003.17 | 0.0051 | 0.0234 | 07/31/2025 |
| 11 | DFA Emerging Markets Core Equity 2 Portfolio | 16,217 | 16,217 | 83,193.21 | 0.0002 | 0.02 | 07/31/2025 |
| 12 | Dimensional Funds II Plc - Emerging Markets Targeted Value Fd. | 14,503 | -518 | 74,400.39 | 0.0111 | 0.0179 | 05/31/2025 |
| 13 | SPDR S&P China ETF | 13,500 | 13,500 | 69,255 | 0.0141 | 0.0167 | 09/30/2025 |
| 14 | CC&L UCITS ICAV - Q Emerging Markets Equity UCITS Fund | 13,287 | 13,287 | 68,162.31 | 0.0042 | 0.0164 | 09/30/2025 |
| 15 | DFA Emerging Markets Sustainability Core 1 Portfolio | 9,306 | 0 | 47,739.78 | 0.0038 | 0.0115 | 07/31/2025 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Ariose Capital Management Ltd. | 1,704,393 | 1,704,393 | 8,743,536.09 | 2.9525 | 2.1072 | 09/30/2025 |
| 2 | Candriam Belgium SA | 1,132,563 | 1,132,563 | 5,810,048.19 | 0.0157 | 1.4003 | 06/30/2025 |
| 3 | SG Americas Securities LLC | 876,353 | 54,312 | 4,495,690.89 | 0.0175 | 1.0835 | 06/30/2025 |
| 4 | Susquehanna Financial Group LLLP | 37,537 | 37,537 | 192,564.81 | 0.0003 | 0.0464 | 06/30/2025 |
| 5 | CreativeOne Wealth LLC | 37,430 | 37,430 | 192,015.9 | 0.0047 | 0.0463 | 06/30/2025 |
| 6 | Geode Capital Management LLC | 54,562 | 32,525 | 279,903.06 | 0 | 0.0675 | 06/30/2025 |
| 7 | Connor, Clark & Lunn Investment Management Ltd. | 27,800 | 27,800 | 142,614 | 0.0004 | 0.0344 | 06/30/2025 |
| 8 | Morgan Stanley & Co. LLC | 58,295 | 23,478 | 299,053.35 | 0.0001 | 0.0721 | 06/30/2025 |
| 9 | Two Sigma Securities LLC | 12,821 | 12,821 | 65,771.73 | 0.0076 | 0.0159 | 06/30/2025 |
| 10 | HRT Financial LP (US) | 25,110 | 9,119 | 128,814.3 | 0.0006 | 0.031 | 06/30/2025 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Stonepine Capital Management LLC | 0 | -483,647 | 0 | 0 | 0 | |
| 2 | Two Sigma Advisers LP | 209,383 | -153,817 | 1,074,134.79 | 0.002 | 0.2589 | 06/30/2025 |
| 3 | UBS Securities LLC | 184,845 | -133,701 | 948,254.85 | 0.0004 | 0.2285 | 06/30/2025 |
| 4 | Two Sigma Investments LP | 113,262 | -97,104 | 581,034.06 | 0.001 | 0.14 | 06/30/2025 |
| 5 | Ground Swell Capital LLC | 0 | -63,730 | 0 | 0 | 0 | |
| 6 | Millennium Management LLC | 0 | -61,478 | 0 | 0 | 0 | |
| 7 | HBK Sorce Advisory LLC | 0 | -46,060 | 0 | 0 | 0 | |
| 8 | abrdn, Inc. | 136,471 | -26,109 | 700,096.23 | 0.0066 | 0.1687 | 06/30/2025 |
| 9 | JPMorgan Securities LLC (Investment Management) | 0 | -5,000 | 0 | 0 | 0 | |
| 10 | Simplex Trading LLC | 0 | -3,229 | 0 | 0 | 0 |
Data provided by FactSet Research Systems Inc.